Volume 38, Issue 3 (Journal of Advanced Materials-Fall 2019)
2019, 38(3): 87-99 |
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Safari N, Toroghinejad M, Kharaziha M, Saeedi V. Influence of Cu Element on Degradation Rate and Biological Properties of Mg-Al-Cu Alloy Prepared by Spark Plasma Sintering. Journal of Advanced Materials in Engineering (Esteghlal) 2019; 38 (3) :87-99
URL: http://jame.iut.ac.ir/article-1-1043-en.html
URL: http://jame.iut.ac.ir/article-1-1043-en.html
1. Department of Materials Engineering, Isfahan University of Technology, Isfahan, Iran. , ngs.safari1991@gmail.com
Abstract: (5097 Views)
The aim of this study was to fabricate the Mg-1Al-Cu alloys with various amounts of Cu content (0, 0.25, 0.5 and 1 wt.%) using spark plasma sintering (SPS) approach and evaluation of their degradation rate and biological properties. The results indicated that Cu incorporation (0.25 wt.%) significantly diminish degradation rate from 0.039 cm/h in pure Mg to 0.00584 cm/h in Mg-1Al-0.25Cu alloy. In addition, Mg-1Al-0.25Cu alloy could noticeably (1.25 times) promote viability of MG63 cells compared to pure Mg, owing to the optimized ion release. Moreover, the antibacterial activity of Mg-1Al-0.25Cu was considerable. In summary, Mg-1Al-0.25Cu alloy with appropriate degradation rate, good biocompatibility and antibacterial properties can be introduced as a biodegradable orthopedic implant.
Type of Study: Research |
Subject:
Biomaterials
Received: 2019/06/19 | Accepted: 2019/08/28 | Published: 2019/12/1
Received: 2019/06/19 | Accepted: 2019/08/28 | Published: 2019/12/1
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