Hydroxyapatite coatings have been used on metallic substrates in a variety of applications, including modifying the surface of human implants, bone osseointegration and biological fixation. In this paper, the effects of various kinds of metallic substrate on clinical and pathological results of in vivo tests are presented. Four kinds of endodontic implants i.e, stainless steel, cobalt base alloy, plasma sprayed hydroxyapatite coated stainless steel, plasma sprayed hydroxyapatite coated cobalt base alloy were prapared and implanted in mandibular canine of cats. After a healing period of 4 months, investigation by SEM and histopathological interpretation and evaluation showed significant differences in tissue response and osseointegration between coated and non-coated metallic implants. It was concluded that the results were affected by the kind of metallic substrate . Keywords: Hydroxyapatite coating, Dental endodontic implant, Osseointegration, Corrosion, Stainless steel, Cobalt base alloy

Keywords: Hydroxyapatite Coating, Dental endodontic implant, Osseointegration, Corrosion, Stainless Steel, Cobalt base alloy

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