Refrigerants that are used in refrigeration systems, cause environmental difficulties such as depletion of ozone layer and greenhouse effect. Thus, we must find substitutes for such refrigerants, in this paper, the effect of refrigerant on the thermodynamics performance of refrigeration cycles are studied. To do this, a refrigerator that has designed for R12, is simulated. Results show that pure refrigerant R134a and mixture R32/R132b are convenient substitutes for R12.

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