In this study, the distribution of heavy metals pollution including arsenic, antimony, nickel, copper, cadmium, cobalt, bismuth, lead and zinc in the stream sediments of Zarshuran- Aghdarreh area was investigated by using statistical techniques and the geometric integration of each sample basin. For this purpose, the degree of pollution in 154 stream sediment samples was analyzed and the distribution maps for enrichment factors were prepared by using a combination technique, pixel estimation, and statistical and geostatistical methods. The results of calculating the enrichment factors indicated that the higher enrichment was related to arsenic, antimony, bismuth, cadmium and lead. Furthermore, the concentration of zinc, copper, lead, arsenic, antimony, cadmium and bismuth in the stream sediment samples was higher than the global average. Application of the principal component analysis on the data led to the recognition of 9 main components for the dataset; the first 5 were components with eigen values greater than 1 and a cumulative percentage more than 85%. Arsenic, antimony, cadmium, lead and zinc in the first component, cobalt in the second component, bismuth in the third component, copper in the fourth component and nickel in the fifth component had the highest values.