Heavy metals are known to have deleterious effects on human health. The main route of human exposure to heavy metals is the daily intake of food. This study was designed to investigate the heavy metal concentrations (Cu, Zn, Mn, Fe, Cr, Ni and Cd) in soil and major food crops (wheat, potato and corn) and estimate the health risks of metals to humans via soil and the crops consumed in Hamedan Province, using the total non-cancer hazard quotient. Daily metal intakes were estimated for three receptor groups and then compared with health guideline values. The non-cancer risk estimations showed that chromium, manganese, cadmium, zinc, Iron, Nickel and copper have oral Hazard Quotient values less than a value of one. The Hazard Index values were greater than 1 for all age groups, suggesting that adults and children in the study area may experience a potential non-cancer risk due to diet of heavy metal via wheat, corn and potato consumption and soil ingestion. Consumption of plant foods particularly wheat was found to be the major route of human exposure to heavy metal. The soil ingestion route is also important.